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Bilirubin, Total (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Your liver’s ability to process bilirubin can signal liver health or conditions like jaundice."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15480-7
Short code
L inter Icter Ab Titr Ser Aggl
Synonyms
L inter Icter Ab Titr Ser Aggl
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
aggl
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a total bilirubin test to check for liver disease, bile duct blockages, or conditions like hemolytic anemia (where red blood cells break down too quickly). It can also help diagnose jaundice, which causes yellowing of the skin and eyes, or monitor treatment for liver problems.

How the Test Works

A blood sample is taken from a vein, usually in your arm. The blood is sent to a lab, where it’s analyzed to measure bilirubin levels. The test doesn’t require fasting unless instructed by your healthcare provider.

What to Expect Before or After

No special preparation is needed, but you may feel slight discomfort from the needle. If you’re nervous, let your healthcare provider know. Results are typically ready within 1–2 days.

Possible Results and Interpretation

Bilirubin levels vary by age, health, and other factors. High levels may indicate liver or bile duct issues, while low levels could suggest certain blood disorders. Your doctor will discuss results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Bilirubin

Frequently asked questions

What causes elevated bilirubin?
Elevated bilirubin can result from liver problems (like hepatitis or cirrhosis), bile duct blockages (e.g., gallstones), or increased red blood cell breakdown (e.g., anemia). It may also appear in newborns due to jaundice.
How long does it take to get results?
Results are usually available within 1–2 business days, depending on your lab’s processing time. Your doctor will explain what the numbers mean in relation to your health.
Can diet affect bilirubin levels?
Diet alone rarely affects bilirubin levels, but certain foods (like fatty foods) may influence bile flow indirectly. Avoiding alcohol or excessive caffeine before the test can help ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy