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Serum/Plasma Total Protein by Bromocresol Green (BCG) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum or plasma, which includes proteins like albumin and globulins. Proteins are essential for maintaining fluid balance, supporting immunity, and transporting nutrients.

Quick summary

["Your blood protein levels help your body function properly and can signal potential health issues if they’re too high or too low."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86705-1
Short code
L intracell Ab Titr Ser IA
Synonyms
L intracell Ab Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Blood proteins play key roles in your body’s health, including keeping fluids in circulation, aiding immune function, and transporting important substances. Abnormal levels may indicate conditions like dehydration, liver disease, kidney problems, or infections.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a liver or kidney evaluation. Avoid heavy meals or alcohol to ensure accurate results.

What the Results Mean

Your doctor will compare your results to standard ranges to check for any imbalances. High protein levels might suggest dehydration, severe infections, or certain cancers, while low levels could point to liver disease, kidney failure, or malnutrition.

Common Reasons for Testing

Doctors order this test to diagnose or monitor conditions like chronic kidney disease, liver disease, malnutrition, or to evaluate fluid balance in severe illness. It’s also used in screening for conditions affecting protein synthesis or breakdown.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated protein levels may reflect conditions such as dehydration, severe infections, or inflammatory diseases, while low levels often signal liver dysfunction, kidney disease, or protein-losing conditions. This test is a simple yet valuable tool for assessing overall protein status in the bloodstream.

Short name

Total Protein (BCG)

Frequently asked questions

What does a high or low protein result mean?
A high protein result could indicate dehydration, severe infections, or conditions like multiple myeloma. A low result may suggest liver disease, kidney problems, or malnutrition. Your doctor will discuss these findings in detail with you.
Does diet affect protein test results?
While diet can influence protein levels in some cases (e.g., high-protein diets), the BCG method is generally reliable. Fasting before the test helps ensure accurate results, especially if your doctor suspects liver or kidney issues.
How often should I get this test?
Your doctor will determine how often you need this test based on your health status. Regular monitoring may be recommended for chronic conditions like kidney or liver disease, but routine screening isn’t typically advised unless you have risk factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy