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Serum Lipase Activity (24-Hour Quantification)

Published: August 9, 2026Updated: August 16, 2026

This test measures how much lipase, an enzyme produced by the pancreas, is present in your blood over a 24-hour period. It helps assess pancreatic function and identify potential issues like pancreatitis.

Quick summary

["Lipase levels can signal pancreatic problems, including inflammation or damage."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25992-9
Short code
Lipase 24h Ur-cCnc
Synonyms
Lipase 24h Ur-cCnc
Category
glucose
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
20
Ref high
400
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82670
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like severe abdominal pain, nausea, vomiting, or unexplained weight loss. It could also be used to monitor chronic conditions affecting the pancreas or to check for complications after a procedure or injury.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood sample drawn from a vein in your arm, typically in a clinic or lab setting. The process usually takes a few minutes, and you can resume normal activities afterward.

What the Results Mean

Higher-than-normal levels of lipase can indicate acute pancreatitis or other pancreatic issues. Lower-than-normal levels might suggest a less common condition or could be due to factors like malnutrition. Your results will be interpreted by your healthcare provider in the context of your overall health and symptoms.

Common Causes and Conditions

Elevated lipase levels are often linked to pancreatitis (inflammation of the pancreas), gallstones blocking the bile duct, or pancreatic tumors. Other conditions, such as kidney disease or certain medications, may also affect lipase levels.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lipase (24-hour)

Frequently asked questions

What are the normal reference ranges for this test?
There is no single standard reference range for 24-hour lipase measurements because it depends on the lab’s method and patient factors. Your healthcare provider will use the results alongside your symptoms and other tests to guide diagnosis and treatment.
Can I eat or drink anything before this test?
No dietary restrictions apply to this test. However, if you are scheduled for a blood draw, inform your provider if you are on blood-thinning medications or have any bleeding disorders.
How soon will I get my results, and what should I do next?
Results are typically available within a few days to a week, depending on the lab. Your healthcare provider will discuss the findings with you and determine the next steps, which may include additional tests or treatments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy