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Lipase (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipase in your blood. Lipase is an enzyme that helps break down fats, and high levels may signal inflammation or digestive issues.

Quick summary

["High lipase levels can indicate pancreatitis or other digestive problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107559-7
Short code
Lipase Drain-cCnc
Synonyms
Lipase Drain-cCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipase?

Lipase is produced by the pancreas and helps digest fats in your digestive system. When the pancreas becomes inflamed (a condition called pancreatitis), it releases more lipase into the bloodstream, which can be detected by this test.

Why Might You Need This Test?

Your doctor may order a lipase test if you have symptoms like severe abdominal pain, nausea, vomiting, or unexplained weight loss. It can also help diagnose conditions like pancreatitis, gallbladder disease, or other digestive disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the test, but this depends on your doctor’s instructions. Bring any medications you’re taking to your appointment.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. The process is quick and typically painless. You may feel a slight pinch, but it usually doesn’t cause long-term discomfort.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lipase Test

Frequently asked questions

What causes elevated lipase levels?
Elevated lipase levels are most commonly caused by pancreatitis, whether acute (sudden) or chronic (long-term). Other possible causes include gallbladder disease, bowel blockages, infections, or certain medications.
How soon will I get my results?
Results are usually available within 24 to 48 hours, depending on your lab. Your doctor will discuss them with you during a follow-up visit.
Can I take my medications before the test?
Yes, you can take your usual medications as scheduled unless your doctor instructs otherwise. Some medications may affect test results, so always check with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy