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Serum Lipase Activity (Enzymatic)

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity of lipase, an enzyme produced by the pancreas that helps break down fats. High levels may indicate pancreatitis or other digestive issues.

Quick summary

["Lipase helps digest fats; elevated levels often signal pancreatitis or pancreatitis-like conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107946-6
Short code
Lipase Pcar-cCnc
Synonyms
Lipase Pcar-cCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a lipase test to diagnose or monitor conditions affecting your pancreas, such as pancreatitis (inflammation of the pancreas), pancreatic cancer, or other digestive disorders. It can also help assess symptoms like severe abdominal pain, nausea, or vomiting that may not have another obvious cause.

What to Expect During the Test

A blood sample is taken from a vein, usually in your arm. You may feel a slight pinch when the needle is inserted, but the procedure is quick. No special preparation is needed unless your doctor instructs otherwise.

Possible Causes of Elevated Lipase Levels

High lipase levels can result from conditions like acute pancreatitis, chronic pancreatitis, pancreatic cysts, or other gastrointestinal issues. Rarely, it may be elevated due to other medical conditions like kidney disease or certain infections.

Possible Causes of Low Lipase Levels

Low lipase levels are less common and may occur in cases of severe liver disease, malnutrition, or certain medications that affect pancreatic function. Your doctor will consider your overall health and symptoms when interpreting results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lipase Test

Frequently asked questions

What does a lipase test tell you about my health?
A lipase test helps identify whether your pancreas is inflamed or damaged. Elevated levels strongly suggest pancreatitis or related conditions. Your doctor will use the results along with your symptoms, medical history, and other tests to make a diagnosis.
How soon will I get my results?
Results are typically available within 24 to 48 hours, depending on your lab. Your doctor will contact you to discuss the findings and next steps.
Can I eat or drink before this test?
No special diet is required, but avoid heavy meals or alcohol 24 hours before the test if instructed by your doctor. Follow any specific instructions they provide to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy