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Pancreatic Lipase Activity (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity of pancreatic lipase, an enzyme produced by the pancreas that helps break down fats. It helps diagnose conditions affecting fat digestion or pancreatic health.

Quick summary

["This test helps identify possible pancreatic or digestive issues by checking enzyme activity in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35316-9
Short code
Lipase sp2 p sincalide Fld-cCnc
Synonyms
Lipase sp2 p sincalide Fld-cCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like abdominal pain, nausea, vomiting, or unexplained weight loss. It can also be used to monitor conditions like pancreatitis or chronic pancreatitis.

What Does a High or Low Level Mean?

Elevated levels may suggest pancreatitis, gallbladder disease, or other digestive disorders. Lower-than-expected levels might indicate pancreatic insufficiency or other rare conditions.

Sample Collection and Preparation

A blood sample is taken from a vein, usually in your arm. The sample is collected in a tube and sent to the lab for testing. This test is typically done on fresh serum or plasma.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions such as acute pancreatitis, chronic pancreatitis, cystic fibrosis, or other pancreatic or gastrointestinal disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pancreatic Lipase

Frequently asked questions

What triggers this test?
Your doctor may recommend this test if you have symptoms like persistent abdominal pain, unexplained digestive issues, or if you have a known risk for pancreatic conditions.
How soon will I get results?
Results are usually available within 1 to 3 business days, depending on lab processing times.
Can I eat or drink before this test?
You may need to fast for 8–12 hours before the test, but your doctor will provide specific instructions based on your situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy