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Pancreatic Amylase (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of amylase, an enzyme produced primarily by the pancreas, in your blood. Amylase helps break down carbohydrates in the digestive system.

Quick summary

["Amylase levels can help diagnose or monitor conditions affecting digestion and pancreas health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35314-4
Short code
Lipase sp4 p sincalide Fld-cCnc
Synonyms
Lipase sp4 p sincalide Fld-cCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like pancreatitis (inflammation of the pancreas), pancreatic cancer, or other digestive issues. It can also help identify problems with the salivary glands or stomach.

What Does a High Level Mean?

Elevated amylase levels often signal acute pancreatitis or other conditions causing pancreatic or salivary gland swelling. However, other factors like certain medications or infections may also raise levels.

What Does a Low Level Mean?

Low amylase levels are less common but may occur with chronic pancreatitis, pancreatic cancer, or severe dehydration. Your provider will consider your symptoms and other test results to interpret results.

How Is This Test Done?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed for amylase concentration using an enzymatic method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Pancreatic Amylase plays a key role in detecting acute pancreatitis, which is a medical emergency requiring prompt attention. Elevated levels can also suggest other gastrointestinal or salivary gland disorders. Chronic pancreatitis or pancreatic cancer may sometimes present with lower levels, though this is less common. Always discuss your results with your healthcare provider, as they will consider your overall health and symptoms for diagnosis.

Short name

Pancreatic Amylase

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on your lab’s processing schedule. Your provider will contact you once they have the results.
Can diet or medications affect my amylase levels?
Certain foods, especially high-carbohydrate meals, can temporarily raise amylase levels. Some medications, like certain antibiotics or diuretics, may also influence results. Always inform your provider about any medications or recent dietary changes.
What should I do if I have unexplained abdominal pain or nausea?
If you experience persistent abdominal pain, nausea, vomiting, or other concerning symptoms, seek medical attention immediately. High amylase levels can indicate serious conditions like pancreatitis, which requires prompt evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy