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Lipoprotein(a) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a) in your blood, a type of cholesterol-related protein that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) is linked to higher heart disease risk; knowing your level helps guide prevention efforts."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
60640-0
Short code
Li-Pg' Skull XR
Synonyms
Li-Pg' Skull XR
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares similarities with LDL (bad cholesterol), it behaves differently in the body and is associated with a higher risk of clotting and cardiovascular events.

Why Is This Test Done?

Your doctor may order this test if you have a family history of early heart disease, certain genetic conditions, or if you’ve had a stroke or heart attack. It can also be part of routine cardiovascular risk assessment.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The test measures the concentration of lipoprotein(a) using a specialized immunoassay method to detect its presence in serum or plasma.

What Do Results Mean?

Higher levels of lipoprotein(a) may increase your risk of heart disease or stroke. While there’s no single reference range, elevated levels often warrant further evaluation or lifestyle/medication adjustments to manage risk.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lip(a)

Frequently asked questions

What causes lipoprotein(a) levels to change?
Lipoprotein(a) levels are generally stable over time and influenced by genetics rather than diet or exercise. However, certain conditions like kidney disease or pregnancy may temporarily affect measurements.
How can I lower lipoprotein(a) levels?
There’s no direct medication to lower lipoprotein(a) yet, but managing other risk factors—such as high blood pressure, smoking cessation, and maintaining a heart-healthy diet—may indirectly support cardiovascular health.
Is this test covered by insurance?
Coverage depends on your doctor’s order and insurance policy. If ordered for cardiovascular risk assessment, check with your provider or insurer for specifics.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy