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Lipoprotein(a) (Lp(a)) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of cholesterol-related protein that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) levels help assess cardiovascular risk beyond traditional cholesterol measures."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70034-4
Short code
Lipophages NFr CSF Manual
Synonyms
Lipophages NFr CSF Manual
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). It’s distinct from other cholesterol types and may play a role in blood clotting and artery plaque buildup. While it’s inherited, levels can sometimes change with lifestyle factors like diet or smoking.

Why Might You Need This Test?

Your doctor may order this test if you have a family history of early heart disease, certain genetic conditions (like hyperhomocysteinemia), or if you’ve had a heart attack or stroke. It’s also used to monitor treatment in some cases.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis using an immunoassay method to measure lipoprotein(a) concentration.

What Do Results Mean?

Results are reported as a numerical value (e.g., mg/dL or mmol/L) representing your lipoprotein(a) level. Higher levels may indicate increased cardiovascular risk, but interpretation depends on your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lp(a) Level

Frequently asked questions

Why is this test important?
Lipoprotein(a) is considered a strong independent risk factor for heart disease, even when other cholesterol levels are normal. It may contribute to artery damage and clotting, making it a key marker for personalized cardiovascular risk assessment.
How does this test differ from other cholesterol tests?
Unlike standard cholesterol tests (like LDL or HDL), lipoprotein(a) is not broken down by diet or exercise and is primarily inherited. It’s measured separately because its impact on heart health is distinct from other lipids.
What lifestyle changes can help?
While there’s no direct treatment for lowering lipoprotein(a), managing other risk factors—such as quitting smoking, controlling blood pressure, and maintaining a heart-healthy diet—can indirectly support cardiovascular health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy