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Lithium Concentration in Blood

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of lithium, a medication, in your blood. Lithium is used to treat certain mental health conditions.

Quick summary

["Lithium levels help doctors monitor your medication dose and prevent potential side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
101751-6
Short code
Lithium Bld ICP/OES-sCnc
Synonyms
Lithium Bld ICP/OES-sCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
0.6
Ref high
1.2
Critical range
— – 1.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
inductively-coupled-plasma-optical-emission-spectrometry-icp-oes
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking lithium to manage conditions like bipolar disorder or depression. Regular testing helps ensure your dose stays safe and effective.

How the Test Works

A blood sample is taken from a vein in your arm. The lithium in your blood is measured using a specialized lab method to check your current medication level.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any other medications or supplements you’re taking, as they could affect lithium levels.

Possible Results and Next Steps

Results are compared to your usual target range, which depends on your condition and dose. Low levels may mean your medication isn’t working, while high levels could require dose adjustments or monitoring.

Reference range

Therapeutic: 0.6-1.2 mmol/LN/A

Specimen: plasma

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lithium Level

Frequently asked questions

What causes lithium levels to change?
Several factors can affect lithium levels, including diet (e.g., salt intake), hydration, kidney function, and other medications. Stress, illness, or changes in your dose can also impact results.
How often should I get this test?
Your doctor will determine the timing based on your treatment plan. Typically, tests are done regularly (e.g., weekly or monthly) to ensure safety and effectiveness.
Can I drink water before the test?
Yes, but avoid excessive salt or diuretics, as they may influence lithium levels. Always follow your doctor’s specific instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy