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Lithium concentration in serum/plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of lithium in your blood, often done to monitor treatment for conditions like bipolar disorder or certain neurological disorders.

Quick summary

["Lithium levels help doctors adjust your medication to avoid side effects or maintain balance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
3721-8
Short code
Lithium Ur-mCnc
Synonyms
Lithium Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
0.6
Ref high
1.2
Critical range
— – 1.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Lithium is a medication used to stabilize mood in conditions such as bipolar disorder. Your doctor may order this test to check if your lithium levels are within the safe range. Too much lithium can cause serious health issues, while too little may not be effective.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the test, but this depends on your doctor’s instructions. Bring any medications you’re currently taking to your appointment.

How the Test Works

A healthcare professional will draw blood from a vein in your arm. The blood sample is then sent to a lab to measure lithium levels using a specialized test method.

What the Results Mean

Results will show your lithium concentration in units typically measured per deciliter (e.g., mg/dL). Your doctor will interpret these results in relation to your symptoms and medical history.

Reference range

Therapeutic: 0.6-1.2 mmol/LN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lithium levels are critical for managing mood disorders. Too high can cause toxicity, leading to symptoms like nausea, confusion, or even seizures. Too low may mean your medication isn’t working as intended. Regular monitoring helps prevent these issues.

Short name

Serum/plasma lithium level

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your treatment plan. Typically, lithium levels are checked every few weeks or months to adjust your dose if needed.
What are common side effects of lithium?
Common side effects may include nausea, dizziness, or increased thirst. If you experience severe symptoms like vomiting, irregular heartbeat, or confusion, seek medical attention immediately.
Can I drink water before the test?
Yes, you can drink water unless your doctor specifies otherwise. Avoid excessive fluids or certain foods that might affect your lithium levels, such as high-sodium diets.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy