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Lithium concentration (serum/plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of lithium in your blood or plasma. Lithium is a mineral often used to treat certain mental health conditions.

Quick summary

["Lithium levels help doctors monitor your treatment and prevent potential side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
25463-1
Short code
Lithium Ur-sCnc
Synonyms
Lithium Ur-sCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
0.6
Ref high
1.2
Critical range
— – 1.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking lithium medication to manage conditions like bipolar disorder or depression. Regular checks help ensure your dose is safe and effective.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or vein to draw blood. If testing urine, you’ll collect a sample over 24 hours.

What the Results Mean

Results help determine if your lithium levels are within the target range for your treatment. Too much or too little can affect how well your medication works or cause side effects.

Common Uses of Lithium Testing

Doctors use this test to adjust your lithium dose, check for toxicity, or assess how well your body is handling the medication over time.

Reference range

Therapeutic: 0.6-1.2 mmol/LN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lithium testing is critical for managing mental health conditions because it helps balance mood and prevents serious complications like seizures or kidney issues.

Short name

Lithium Level

Frequently asked questions

What causes lithium levels to be checked regularly?
Regular checks are done to ensure your lithium levels stay within the safe range, especially if you’re new to the medication, have kidney problems, or are taking other medications that interact with lithium.
What are the typical symptoms of lithium toxicity?
Symptoms may include nausea, vomiting, confusion, tremors, or irregular heartbeat. If you experience these, seek medical attention immediately.
Can diet or lifestyle affect lithium levels?
Yes, factors like dehydration, certain foods, or other medications can influence lithium levels. Always follow your doctor’s advice on diet and supplements while on lithium.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy