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Serum/Plasma Line Blot Immunoassay for Liver Cytosolic Proteins

Published: August 9, 2026Updated: August 16, 2026

This test measures specific proteins found in liver cell cytoplasm, often used to assess liver function or detect abnormalities in protein expression.

Quick summary

["Helps doctors evaluate liver health and identify potential protein-related issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82921-8
Short code
Liver Cytosol IgG Ser Ql Line blot
Synonyms
Liver Cytosol IgG Ser Ql Line blot
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
line-blot
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a line blot immunoassay to detect and quantify multiple proteins extracted from your liver cells. This method identifies specific proteins that may be elevated or altered due to liver disease, genetic conditions, or other metabolic processes.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, jaundice, or unexplained liver enzyme abnormalities. It can also be used in research or specialized diagnostic scenarios where detailed protein profiling is needed.

Common Uses in Clinical Practice

While less common than standard liver function tests, this test can support investigations into rare liver diseases, hereditary protein disorders, or conditions affecting protein synthesis in the liver.

Sample Collection and Preparation

Blood is drawn from a vein, typically in your arm. The sample is processed to isolate liver cytosolic proteins, which are then analyzed using the line blot immunoassay method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns in liver cytosol may indicate conditions such as metabolic liver diseases, genetic disorders (e.g., alpha-1 antitrypsin deficiency), or chronic liver inflammation. Early detection can guide treatment decisions and monitor disease progression.

Short name

Liver Cytosolic Protein Profile (Line Blot)

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result may suggest an underlying liver issue affecting protein production or metabolism. Your doctor will interpret results in the context of your symptoms, medical history, and other test findings.
How long does it take to get results?
Results are typically available within 2–5 business days, depending on lab processing times and any additional confirmatory testing required.
Is fasting required for this test?
No fasting is required, as this test focuses on proteins rather than blood sugar or lipid levels. However, always follow your healthcare provider’s instructions for sample collection.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy