Skip to content

Protein Electrophoresis (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood, helping identify abnormalities in protein levels that may indicate conditions like multiple myeloma, liver disease, or kidney problems.

Quick summary

["Protein electrophoresis helps diagnose and monitor conditions affecting blood proteins."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32684-3
Short code
LMWH PPP-aCnc
Synonyms
LMWH PPP-aCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates blood proteins based on size and electrical charge, revealing distinct bands corresponding to albumin, globulins (including immunoglobulins), and other proteins. This helps assess protein balance and identify potential imbalances.

Why Is This Test Done?

Your healthcare provider may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or signs of organ dysfunction. It’s also used to monitor conditions like multiple myeloma, liver disease, or kidney disease.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The blood is processed to separate serum or plasma, which is then analyzed in a lab using electrophoresis to separate proteins.

Common Conditions Evaluated

This test helps detect conditions such as monoclonal gammopathy (abnormal protein spikes), hypoalbuminemia (low albumin), or elevated globulins (e.g., in chronic inflammation or autoimmune diseases).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Protein electrophoresis is critical for diagnosing and managing diseases affecting protein synthesis, distribution, or clearance in the body. It provides a detailed profile of blood proteins that can guide treatment decisions, especially in oncology, hematology, and organ-related disorders.

Short name

Protein Electrophoresis

Frequently asked questions

What does a protein electrophoresis test show?
It shows the relative amounts of different proteins in your blood, including albumin, globulins, and any abnormal spikes or dips that may indicate underlying health issues.
How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on lab processing times.
Can I eat or drink anything before this test?
No special preparation is needed for this test. However, inform your healthcare provider about any medications or supplements you’re taking, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy