Serum Protein Electrophoresis Pattern (Screening)

Why Is This Test Done?

Your doctor may order this test if they suspect conditions affecting protein levels, such as kidney disease, liver problems, or certain cancers. It’s also used to monitor treatment progress for conditions like multiple myeloma or to check for signs of chronic inflammation or infection.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process takes just a few minutes, and you can resume normal activities afterward. If you’re on blood thinners or have a history of bleeding issues, let your doctor know.

What Happens During the Test?

The blood sample is sent to a lab where it’s separated into different protein fractions using an electric field. This creates a pattern of bands that represent various proteins, such as albumin, globulins, and others. The pattern helps identify any unusual spikes or dips that may indicate health concerns.

What Are Common Findings?

Normal results show a balanced distribution of proteins. Abnormal patterns may include an increased or decreased amount of certain proteins, such as a high gamma globulin level (often seen in multiple myeloma) or an abnormal albumin-to-globulin ratio (possible liver or kidney issues).