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C-reactive protein (CRP) by nephelometry (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps track inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
64970-7
Short code
London Plane (rPla a) 3 IgE Qn
Synonyms
London Plane (rPla a) 3 IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker that signals your body’s immune response. High levels may indicate inflammation, which can be caused by infections, injuries, or certain health conditions like arthritis or heart disease. Your doctor may use this test to check for early signs of problems or to monitor treatments.

How the Test Works

A small blood sample is taken from your arm and sent to a lab. The lab uses a special method called nephelometry to measure the amount of CRP in your blood. This test helps healthcare providers detect and track inflammation without needing invasive procedures.

Common Reasons for Testing

Doctors often order CRP tests to diagnose or monitor conditions like infections (such as pneumonia or urinary tract infections), autoimmune diseases (like rheumatoid arthritis), or to check for signs of inflammation after surgery or injury. It may also be used to evaluate heart disease risk or response to treatment.

What to Expect Before the Test

You can eat, drink, and move around normally before the test. No special preparation is needed, but let your doctor know if you’re on blood thinners or have any allergies. Avoid strenuous activity 24 hours before testing if your doctor advises it, as it may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP as a Diagnostic and Monitoring Tool

Short name

CRP (Nephelometry)

Frequently asked questions

What does a high CRP level mean?
A high CRP level often means your body is fighting inflammation. While it can be normal after an infection or injury, persistent high levels may signal chronic conditions like arthritis, heart disease, or other autoimmune disorders. Your doctor will consider your symptoms and other test results to interpret the results accurately.
Can CRP levels change with diet or exercise?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. For example, a healthy diet rich in fruits, vegetables, and omega-3 fatty acids may help lower inflammation. Regular physical activity can also support lower CRP levels, but results vary by individual. Always discuss lifestyle changes with your doctor.
How often should I get a CRP test?
Your doctor will determine how often you need a CRP test based on your health condition and treatment plan. Some people may need it monthly, quarterly, or annually, depending on their diagnosis. Regular monitoring helps track changes in inflammation and adjust treatments as needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy