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Serum or Plasma Loperamide Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the opioid loperamide in your blood or plasma/serum. Loperamide is used to treat diarrhea and may be present in your system after taking this medication.

Quick summary

["Knowing your loperamide level helps doctors monitor how your body is processing the drug."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73298-2
Short code
Loperamide ind plt IgM SerPl Ql FC
Synonyms
Loperamide ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking loperamide and experiencing unusual side effects, such as excessive drowsiness, confusion, or slow heart rate. It may also be used to assess drug levels in specific cases, like overdose evaluation or therapeutic drug monitoring.

What to Expect Before the Test

No special preparation is needed. You may have blood drawn from a vein in your arm, typically in a lab setting. If you’re taking loperamide, it’s important to inform your doctor or technician beforehand.

What the Test Results Mean

Results are interpreted by your healthcare provider based on your medical history, symptoms, and other factors. High levels may indicate overdose or improper metabolism, while low levels might suggest insufficient medication absorption.

Common Uses and Considerations

This test is primarily used in clinical settings where precise drug monitoring is critical, such as in cases of suspected overdose, drug interactions, or unusual reactions to loperamide.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Loperamide is an opioid used to slow bowel movements in diarrhea. Abnormal levels can affect its effectiveness or pose risks like respiratory depression. Your doctor will assess results in the context of your symptoms and medical history.

Short name

Loperamide Level

Frequently asked questions

Why might my doctor request this test?
Your doctor may order this test if you’re experiencing symptoms that could be linked to loperamide levels, such as severe drowsiness, irregular heartbeat, or persistent diarrhea despite treatment. It may also be used in specialized cases, like monitoring in patients with kidney or liver issues.
What are typical reference ranges?
Reference ranges for loperamide levels vary by lab and patient factors. Your results will be compared to a range specific to your healthcare provider’s standards, not a general public range.
How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Follow-up with your doctor if you have questions or concerns about your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy