Skip to content

C-reactive protein (CRP) mass concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of C-reactive protein in your blood, a protein produced by your liver in response to inflammation.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
28406-7
Short code
LOSSOFINDEPENDENCE
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
reported-living-hiv
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker for inflammation, which your body produces as a defense against injury, infection, or illness. High levels may signal an active inflammatory process, such as an infection, injury, or certain diseases like rheumatoid arthritis or heart disease. Your doctor may order this test to check for inflammation or to monitor treatment progress.

When You Might Need This Test

Your doctor might recommend a CRP test if you have symptoms of inflammation (like fever, pain, or swelling), if you have a known condition linked to inflammation, or if you’re recovering from surgery, an infection, or a medical procedure. It can also be used to track how well a treatment is working.

What to Expect Before the Test

This test is usually done by drawing blood from a vein in your arm. You may feel a slight pinch, but it’s quick and painless. No special preparation is needed unless your doctor instructs otherwise. Avoid strenuous activity or eating heavy meals 24 hours before the test if directed.

What the Results Mean

Results are interpreted based on your overall health and symptoms. Very low levels may indicate no active inflammation, while higher levels could point to an underlying issue. Your doctor will discuss the results with you in the context of your medical history and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a key tool for diagnosing and managing conditions involving inflammation. It helps doctors distinguish between infections, autoimmune diseases, and other inflammatory conditions. Elevated CRP levels can also signal risks for heart disease or other chronic inflammatory disorders, prompting further evaluation or treatment adjustments.

Short name

CRP

Frequently asked questions

What causes CRP levels to be high?
CRP can rise due to infections (like pneumonia or urinary tract infections), injuries, surgeries, or autoimmune diseases (like lupus or rheumatoid arthritis). Stress, certain medications, or even minor illnesses can also temporarily increase CRP levels. Your doctor will consider these factors when interpreting your results.
How often should I get this test?
The frequency depends on your health condition. If you have a chronic illness like heart disease or arthritis, your doctor may order CRP tests regularly to monitor your inflammation levels. If you’re healthy, this test might not be routine unless you have symptoms or risk factors.
Can diet or lifestyle affect CRP levels?
Yes! A healthy diet rich in fruits, vegetables, and omega-3 fatty acids (like those in fish) can help lower inflammation. Regular exercise, managing stress, and avoiding smoking or excessive alcohol may also support lower CRP levels. Small lifestyle changes can sometimes reduce inflammation over time.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy