Serum or Plasma Substance Concentration (General Protein or Peptide Profile) – 24-Hour Fluid Collection
This test measures specific proteins or peptides in your blood or urine over a 24-hour period to help assess their levels in your body.
["Understanding your protein or peptide levels can help identify health concerns early."]
Key facts at a glance
- LOINC
- 28407-5
- Short code
- LOTSOFREGRETS
- Synonyms
- —
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- reported-living-hiv
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
This test evaluates the concentration of certain proteins or peptides in your body fluids, which may include blood serum/plasma or urine. The 24-hour collection helps capture consistent levels over time, rather than just a single sample. The exact proteins or peptides tested depend on the specific profile requested by your healthcare provider.
Why It’s Done
Your doctor may order this test to diagnose or monitor conditions affecting protein metabolism, kidney function, liver health, or other systemic processes. It can also help track responses to treatments or identify unusual protein patterns in your body.
Sample Collection Process
You’ll need to collect urine over a full 24-hour period, typically starting after you urinate in the morning. Your healthcare team will provide instructions on timing and storage to ensure accurate results. Blood samples may also be taken at specific intervals if part of the profile involves serum/plasma.
Preparation and Restrictions
Follow your doctor’s instructions carefully. Avoid certain medications or foods that might interfere with results. For urine collection, keep the sample refrigerated and complete the full 24-hour period to ensure reliable data.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal levels of specific proteins or peptides can signal underlying health issues, such as kidney disease, liver dysfunction, inflammation, or metabolic disorders. For example, elevated or low levels may indicate conditions like proteinuria (protein in urine), hypoalbuminemia (low protein in blood), or other systemic imbalances. Your doctor will interpret results in the context of your medical history and symptoms.
Frequently asked questions
How long will I need to collect urine for this test?
Can I eat or drink anything before or during urine collection?
What if I miss part of the 24-hour urine collection?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy