Skip to content

Lipoprotein(a) [Lp(a)] concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a), a type of cholesterol-like substance in your blood that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) is linked to higher heart disease risk; knowing your levels helps assess cardiovascular health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
60344-9
Short code
LPa MFr SerPl
Synonyms
LPa MFr SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). Unlike regular cholesterol, Lp(a) has a strong genetic influence and may persist at higher levels over time. It’s often considered an independent risk factor for cardiovascular events, such as heart attacks and strokes, even when other cholesterol levels are normal.

Why Is This Test Done?

Your doctor may order this test if you have a family history of heart disease, high cholesterol, or other risk factors. It may also be recommended for people with certain conditions like aortic stenosis or those undergoing preventive cardiovascular screening.

How Is the Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed using a specialized immunoassay method to measure Lp(a) levels.

What Do Results Mean?

Results provide a specific measurement of Lp(a) in milligrams per deciliter (mg/dL). While there are no strict reference ranges for everyone, higher levels are associated with increased cardiovascular risk. Your doctor will interpret results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lipoprotein(a) (Lp(a))

Frequently asked questions

How often should I get this test?
There is no standard schedule for this test. Your doctor will determine if and when to repeat it based on your risk profile, medical history, and other test results.
Can lifestyle changes affect Lp(a) levels?
While diet, exercise, and other lifestyle factors can influence cholesterol levels, Lp(a) is primarily genetically determined. However, some studies suggest certain diets or medications may have a modest effect, but results vary widely among individuals.
Is this test covered by insurance?
Coverage depends on your insurance plan and the reason for testing. If recommended by your doctor for preventive care or managing a known risk, it may be covered. Always confirm with your insurance provider or ask your doctor to provide a detailed explanation of costs.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy