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Serum or Plasma Substance Concentration (Mass) – C-Reactive Protein (CRP)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body. CRP helps doctors assess whether inflammation is present and guide treatment decisions.

Quick summary

["CRP helps track inflammation, often used alongside other tests to diagnose or monitor conditions like infections, autoimmune diseases, or heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43583-4
Short code
LPa SerPl-sCnc
Synonyms
LPa SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker for inflammation, which is the body’s natural response to injury, infection, or illness. High CRP levels may signal an active inflammatory process, such as infections, autoimmune diseases (e.g., rheumatoid arthritis), or conditions like heart disease. Doctors use CRP to monitor how well treatments are working or to check for recurring issues.

When This Test Is Ordered

Your doctor may order a CRP test to evaluate symptoms like fever, joint pain, or swelling, or to monitor chronic conditions. It’s also used before surgeries, during pregnancy, or to assess risk for heart disease. Some tests are done as part of routine check-ups or to guide decisions about medications.

What to Expect Before the Test

No special preparation is needed for this test. You may have blood drawn from a vein in your arm, or a sample of plasma/serum may be collected if you’re already undergoing a blood draw for another test. If you’re taking blood thinners, let your doctor know before the test.

What the Results Mean

Results are reported in milligrams per liter (mg/L). A low CRP level (typically below 1 mg/L) suggests little to no inflammation. Higher levels may indicate an active inflammatory process, but results alone don’t diagnose a specific condition. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Serum/Plasma)

Frequently asked questions

How often should I get this test?
The frequency depends on your health status. If you have a chronic condition like arthritis or heart disease, your doctor may recommend regular CRP checks. For acute issues (e.g., infections), tests may be done more frequently to monitor progress. Ask your doctor about your specific schedule.
Can I eat or drink before this test?
No restrictions apply. You can eat, drink water, and take medications as usual unless your doctor advises otherwise. Fasting isn’t required for CRP testing.
Does this test interact with any medications?
Some medications, like blood thinners (e.g., warfarin) or steroids, may affect CRP levels. If you’re on these or other medications, mention them to your doctor before the test to avoid delays or adjustments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy