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Lipoprotein Subfraction Analysis (Serum) – Quantitative Profile

Published: August 9, 2026Updated: August 16, 2026

This test measures specific types of fats (lipoproteins) in your blood, including cholesterol and triglycerides, to assess heart health and risk of cardiovascular disease.

Quick summary

["Understanding your lipid profile helps manage cholesterol and reduce artery-clogging risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57992-0
Short code
L pneumo 1+3+4+5+6+8 Ab Ser Ql
Synonyms
L pneumo 1+3+4+5+6+8 Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to evaluate your risk of heart disease, monitor existing conditions like high cholesterol, or check for metabolic disorders. It’s often part of routine check-ups or follow-ups for conditions like diabetes or high blood pressure.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 12 hours before the blood draw. Your doctor will provide specific instructions if applicable.

How the Test Works

Blood is drawn from a vein, usually in your arm. The sample is then analyzed to separate and measure different lipoprotein types, including low-density lipoproteins (LDL), high-density lipoproteins (HDL), and very low-density lipoproteins (VLDL).

What the Results Mean

Results show the amounts of various lipoproteins, helping identify high or low levels that may affect heart health. Your doctor will interpret these results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lipid Panel (Subfractions)

Frequently asked questions

High levels of LDL or VLDL can increase the risk of plaque buildup in arteries, leading to heart disease or stroke. Low HDL may also raise risk. This test helps guide treatment plans, such as diet, exercise, or medication to improve lipid levels.
What does a high or low level of any lipoprotein mean?
High levels of LDL or VLDL may signal an increased risk of cardiovascular issues, prompting lifestyle changes or medical interventions. Low HDL levels may also raise concerns, as HDL helps remove cholesterol from arteries. Your doctor will discuss these findings with you.
Yes, diet, exercise, and weight management can significantly impact lipoprotein levels. Small, sustainable changes—like reducing saturated fats, increasing fiber, and staying active—can improve your lipid profile over time.
How often should I get this test?
Your doctor will determine how often you need this test based on your health status, risk factors, and medical history. Typically, it’s recommended every 1–5 years for adults without known heart disease, or more frequently if you have risk factors or existing conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy