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Lung-specific protein antigen (neopterin) in urine, measured by turbidimetry

Published: August 9, 2026Updated: August 16, 2026

This test measures a substance called neopterin in your urine. Neopterin is produced when your body fights infections, particularly those caused by certain viruses or immune system overactivity.

Quick summary

["Neopterin helps assess immune response and inflammation in the lungs or respiratory system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110365-4
Short code
L pneumo1 Ag Msmt Ur
Synonyms
L pneumo1 Ag Msmt Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent cough, shortness of breath, or other signs of lung infection or inflammation. It can also be used to monitor conditions like tuberculosis, certain cancers, or immune-related lung diseases.

What to Expect Before the Test

No special preparation is needed. You’ll likely provide a urine sample, often collected at home or in a clinic. Follow your provider’s instructions carefully to ensure accurate results.

What the Results Mean

Higher than expected levels of neopterin may indicate an active immune response, such as infection or inflammation. Lower levels might suggest a less active immune response or normal conditions. Your provider will interpret results in the context of your overall health and symptoms.

Common Conditions Monitored

This test is often used to monitor conditions like tuberculosis, certain viral infections, or immune-mediated lung diseases. It can also help track responses to treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Neopterin Urine Test

Frequently asked questions

What causes elevated neopterin levels?
Elevated neopterin levels are often linked to viral infections, immune system activation, or inflammatory processes in the body. In the lungs, it may reflect conditions like tuberculosis, certain viral pneumonias, or immune-related lung diseases.
Can this test be used to diagnose lung cancer?
This test is not typically used as a primary diagnostic tool for lung cancer. However, it may be part of a broader evaluation if you have symptoms or risk factors for lung diseases, including cancer-related inflammation.
How long does it take to get results?
Results are usually available within a few days to a week, depending on your lab’s processing time. Your healthcare provider will contact you once they have the results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy