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Lung-specific protein antigen (e.g., surfactant protein) in urine, measured by immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test detects proteins produced by lung tissue, often used to check for lung damage or infection in urine samples.

Quick summary

["Helps identify possible lung-related conditions through urine analysis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41499-5
Short code
L pneumo1 Ag Ur Ql IA
Synonyms
L pneumo1 Ag Ur Ql IA
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for specific proteins (like surfactant proteins A and B) that are normally found in lung tissue. When the lungs are injured or inflamed, these proteins can enter the bloodstream and appear in urine. This test helps doctors assess conditions such as pneumonia, lung infections, or other lung diseases.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like shortness of breath, persistent cough, or if you’ve been diagnosed with a lung condition. It’s also used in research or specialized settings to monitor lung health in certain clinical scenarios.

Common Conditions Monitored

This test is less commonly used in routine care but may be part of specialized evaluations for conditions like acute respiratory distress syndrome (ARDS), severe pneumonia, or interstitial lung diseases.

Sample Collection and Preparation

A clean-catch urine sample is typically collected in the morning. You may be instructed to wash your hands and clean the urinary opening before urinating into a sterile container. The sample is then sent to a lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine SP-A/B antigen

Frequently asked questions

How long will results take to get?
Results are usually available within 24 to 72 hours, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
What do abnormal results mean?
Elevated levels of these proteins in urine may suggest lung injury, infection, or inflammation. However, false positives can occur, so results are interpreted in the context of your symptoms and medical history.
Can I take anything before the test?
No special preparations are needed, but avoid excessive fluid intake just before testing if instructed by your provider to ensure a concentrated urine sample.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy