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Lipopolysaccharide (LPS) Antibody Screening in Serum/Plasma by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies that your immune system produces in response to bacterial lipopolysaccharides (LPS), which can be found in certain bacteria. It helps identify if your body has detected and reacted to these substances.

Quick summary

["This test may help diagnose or monitor conditions related to immune responses to bacterial infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17072-0
Short code
L pneumo8 Ab Ser Ql
Synonyms
L pneumo8 Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Lipopolysaccharides (LPS) are complex molecules found on the surface of certain bacteria. When your immune system encounters these molecules, it can produce antibodies specific to them. This test detects the presence of these antibodies in your blood, which can indicate an immune response to bacterial exposure.

Why Might You Need This Test?

Doctors may order this test if you have symptoms suggestive of an immune response to bacterial infection, such as persistent inflammation, unexplained fevers, or conditions like sepsis, autoimmune diseases, or chronic infections. It can also be used in research or clinical studies involving immune monitoring.

What to Expect Before the Test

No special preparation is usually needed for this test. You may have a small needle inserted into a vein in your arm to draw a blood sample. If you are on blood-thinning medication or have a history of bleeding disorders, let your healthcare provider know before the test.

What to Expect During the Test

The blood sample will be collected in a tube and sent to a lab for analysis. The immunoassay method detects antibodies against LPS, which are then measured to determine the presence and level of these antibodies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

LPS Antibody Screen

Frequently asked questions

What are the normal results?
There are no standard reference ranges provided for this test because the interpretation depends on clinical context, patient history, and symptoms. Your healthcare provider will evaluate the results in relation to your overall health and medical needs.
Can this test be used to diagnose bacterial infections?
No, this test does not diagnose bacterial infections directly. It measures antibodies related to bacterial exposure, which can be part of a broader evaluation. A combination of clinical findings, symptoms, and other diagnostic tests is typically used for diagnosis.
How soon will I get my results?
Results are usually available within a few days to a week, depending on the lab’s processing time. Your healthcare provider will contact you with the results and discuss them in detail.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy