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Lipoprotein Subfraction Analysis (Serum) by Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures different types of fats (lipoproteins) in your blood, which help identify how cholesterol is distributed among various particles.

Quick summary

["Helps assess heart health by identifying unhealthy cholesterol patterns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75437-4
Short code
LPN Note
Synonyms
LPN Note
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
licensed-practical-nurse
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Heart Health

Lipoproteins carry cholesterol throughout your bloodstream. Some types, like low-density lipoproteins (LDL), can build up in arteries over time, increasing heart disease risk. This test helps doctors spot these patterns early.

What to Expect Before the Test

You’ll likely have a simple blood draw from a vein in your arm. No special preparation is needed, but fasting may be required depending on your specific test instructions.

Common Uses of the Test

Doctors use this test to evaluate cholesterol levels, diagnose conditions like high cholesterol or heart disease, and guide treatment plans for managing lipid disorders.

What the Results Typically Mean

Results show proportions of different lipoprotein types, helping identify whether you have high levels of harmful particles (e.g., small, dense LDL) or low levels of protective particles (e.g., high-density lipoproteins).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lipoprotein Profile

Frequently asked questions

What does a ‘lipoprotein profile’ measure exactly?
It measures the concentration of various lipoprotein particles (e.g., very low-density lipoproteins, LDL, intermediate-density lipoproteins, high-density lipoproteins) in your blood, often using electrophoresis to separate them.
Do I need to fast before this test?
Some tests may require fasting, but others do not. Always check with your healthcare provider or lab for specific instructions based on your order.
Can this test detect all types of cholesterol?
Yes, it provides a detailed breakdown of lipoprotein classes, helping assess cholesterol distribution beyond simple total cholesterol measurements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy