Skip to content

Rate of erythrocyte sedimentation (ESR) in whole blood

Published: August 9, 2026Updated: August 16, 2026

This test measures how quickly red blood cells settle in a sample of whole blood over time. It can help assess inflammation or infection in your body.

Quick summary

["ESR helps detect inflammation, often used alongside other tests for conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45361-3
Short code
LPT 0.25 ug PW Bld-nRate
Synonyms
LPT 0.25 ug PW Bld-nRate
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is ESR Rate Testing Used For?

ESR rate testing is commonly used to monitor conditions involving inflammation, such as infections (e.g., bacterial or viral), autoimmune diseases (e.g., rheumatoid arthritis, lupus), or inflammatory disorders (e.g., inflammatory bowel disease). It can also be part of routine check-ups for certain symptoms like fatigue, joint pain, or unexplained fevers.

How Is ESR Rate Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The blood is placed in a test tube with an anticoagulant to prevent clotting. The sample is then mixed and allowed to sit undisturbed for a set period (usually 1 hour). The rate at which red blood cells settle to the bottom of the tube is measured and recorded as the ESR rate.

What Does an ESR Rate Result Mean?

An elevated ESR rate often indicates inflammation or infection, but it can also be influenced by factors like age, sex, pregnancy, or certain medications. A normal ESR rate doesn’t definitively rule out inflammation, so it’s usually interpreted alongside other clinical findings and tests.

Common Conditions Monitored With ESR Rate

ESR rate is frequently used to track progression or response to treatment in conditions like rheumatoid arthritis, ankylosing spondylitis, or other autoimmune diseases. It may also be checked during infections, postoperative assessments, or to monitor chronic inflammatory conditions.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

ESR Rate

Frequently asked questions

Why might my doctor order an ESR rate test?
Your doctor may order an ESR rate test to investigate symptoms like persistent fatigue, joint pain, fever, or swelling. It can also be used to monitor chronic conditions or assess how your body responds to treatment for inflammation or infection.
Can an ESR rate test diagnose a specific condition?
No, an ESR rate test alone cannot diagnose a specific condition. It provides a general indicator of inflammation and is often used alongside other tests, such as blood counts, imaging studies, or clinical symptoms, to guide further evaluation.
How often should I get an ESR rate test?
The frequency of ESR rate testing depends on your medical condition and your doctor’s recommendations. Some people may need it annually or more often if they have chronic inflammatory diseases, while others may only need it periodically based on their symptoms or treatment plan.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy