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Bilirubin, Total (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Your liver plays a key role in bilirubin processing; abnormal levels may signal liver or bile duct issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58726-1
Short code
LPT 0.50 ug PW Act/Nor Bld
Synonyms
LPT 0.50 ug PW Act/Nor Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to check for liver disease, bile duct blockages, or conditions like hemolytic anemia (where red blood cells break down too quickly). It can also help diagnose jaundice, a condition where your skin or eyes turn yellow due to high bilirubin levels.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process is quick and usually painless. If you’re nervous, let your healthcare provider know—they can offer comfort measures.

What the Results Mean

Results are compared to a general range, but your specific range depends on your health and lab standards. High levels may indicate liver problems, while low levels could suggest liver disease or other conditions affecting bilirubin processing.

Common Conditions Linked to Bilirubin Levels

Elevated bilirubin can signal liver diseases (like hepatitis or cirrhosis), bile duct obstructions, or red blood cell disorders. Low levels may be normal, but they can also hint at liver dysfunction or certain medications.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Bilirubin

Frequently asked questions

What causes my bilirubin to be high?
High bilirubin often results from liver issues (e.g., inflammation, scarring), blockages in the bile ducts, or rapid red blood cell destruction. Symptoms like jaundice (yellowing skin/eyes) may appear if levels rise significantly. Always discuss symptoms with your doctor.
Will diet affect my bilirubin test results?
Dietary changes alone won’t alter bilirubin levels, but certain foods (like high-fiber or cruciferous veggies) may interact with liver function indirectly. Follow your doctor’s advice for any dietary restrictions tied to your test.
Can I take anything before the blood draw?
Typically, no fasting is required, but avoid alcohol or certain medications (like pain relievers) for 24 hours before testing, as they may affect liver function or test accuracy. Ask your lab for specifics.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy