Skip to content

Serum or Plasma Protein Electrophoresis (Bromocresol Green Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood, often used to identify abnormalities like infections, inflammation, or certain blood disorders.

Quick summary

["Protein electrophoresis helps diagnose conditions affecting blood protein balance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58731-1
Short code
LPT 0.5 ug PHA Act/Nor Bld
Synonyms
LPT 0.5 ug PHA Act/Nor Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Proteins Does This Test Measure?

Electrophoresis separates blood proteins into groups based on their electrical charge. Key fractions include albumin, alpha-globulins, beta-globulins, and immunoglobulins (like IgG and IgA). These proteins play roles in immunity, fluid balance, and transport of nutrients.

Why Might You Need This Test?

Your doctor may order this test to check for conditions like multiple myeloma, Waldenström macroglobulinemia, chronic liver disease, or severe infections. It can also help monitor treatment responses for blood disorders.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. The serum or plasma is then separated and analyzed using bromocresol green dye to detect protein patterns.

What Are Common Findings?

Abnormal bands or shifts in protein patterns may indicate excess proteins (e.g., monoclonal spikes in myeloma), low albumin (common in liver disease), or elevated globulins (linked to inflammation or immune disorders).

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Protein Electrophoresis

Frequently asked questions

Why do some patients get this test even if they don’t have obvious symptoms?
Your doctor may recommend it as part of routine screening, especially if you have a family history of blood disorders, symptoms like fatigue or unexplained weight loss, or conditions like kidney disease or liver problems. It helps detect subtle changes early.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your healthcare provider will help interpret the findings in the context of your health.
Can lifestyle changes affect protein electrophoresis results?
While diet and exercise generally don’t directly alter protein electrophoresis patterns, severe illnesses (e.g., infections, malnutrition) or medications (e.g., steroids) may influence protein levels. Avoiding alcohol and certain medications for a few days before testing can help ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy