Albumin to Creatinine Ratio (ACR) or Urinary Albumin-to-Creatinine Ratio (UACR)

Why This Test Matters

Kidneys normally filter waste and excess substances from your blood. If kidney disease is present, small proteins like albumin may leak into urine. The UACR helps track kidney function by comparing protein loss to muscle waste, which remains stable. Early detection can help manage conditions like diabetes or high blood pressure.

How the Test Works

A small urine sample is collected, typically over a 24-hour period or a single random sample. The lab measures albumin and creatinine levels using a sensitive immunoassay or nephelometry method. The ratio helps identify abnormal protein loss that may signal kidney issues.

When You Might Need It

Doctors order this test if you have risk factors for kidney problems, such as diabetes, high blood pressure, family history of kidney disease, or symptoms like swelling, fatigue, or frequent urination. It’s also used to monitor kidney health in people with chronic conditions.

What to Expect

You’ll collect a urine sample at home (24-hour or random) or provide a sample at a lab. No special preparation is needed, but drinking extra water may help if collecting a 24-hour sample. The test is quick and painless, with results available within a few days.