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Serum or plasma concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.

Quick summary

["Your bilirubin levels can signal liver or blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61351-3
Short code
LPT 0.6 ug PW Bld
Synonyms
LPT 0.6 ug PW Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to check for liver diseases, such as hepatitis or cirrhosis, or to diagnose conditions like jaundice (yellowing of the skin and eyes). It can also help identify blockages in the bile ducts or certain blood disorders.

What to Expect Before the Test

No special preparation is needed. You may have blood drawn from a vein in your arm, or a urine sample may be collected if testing urine bilirubin levels. If you’re taking medications that affect bilirubin, let your doctor know.

How the Test Works

Blood is drawn and sent to a lab, where it is analyzed to measure bilirubin levels. If urine is tested, it is checked for bilirubin presence. The test helps determine whether bilirubin is being processed normally by the liver.

Common Conditions Monitored

High bilirubin levels may indicate liver disease, hemolytic anemia (where red blood cells break down too quickly), or gallbladder issues. Low levels are less common but can occur with certain liver conditions or medications.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin

Frequently asked questions

What causes high bilirubin levels?
High bilirubin can result from liver problems (like hepatitis), blockages in the bile ducts, or conditions that cause red blood cells to break down faster than the liver can process bilirubin.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow-up with your doctor if you have concerns about your results.
Can diet affect bilirubin levels?
Dietary changes alone won’t significantly alter bilirubin levels, but certain foods (like high-fiber or fatty foods) may affect bile flow indirectly. Always discuss dietary concerns with your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy