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Serum/plasma rate of bile acid excretion (or bile acid clearance rate)

Published: August 9, 2026Updated: August 16, 2026

This test measures how quickly bile acids are removed from your bloodstream, which helps assess liver function and bile flow.

Quick summary

["This test evaluates liver function and bile drainage efficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45365-4
Short code
LPT 10 ug CA Bld-nRate
Synonyms
LPT 10 ug CA Bld-nRate
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like jaundice (yellowing of skin/eyes), unexplained fatigue, or signs of liver disease. It may also be used to monitor conditions like bile duct blockages or liver cirrhosis.

What Does the Result Mean?

A slower-than-expected excretion rate may indicate problems with bile production, liver function, or blockages in the bile ducts. Results may vary based on individual health and medical history.

Sample Preparation and Testing Process

A blood sample is drawn, and bile acids are measured using a specialized method (likely enzymatic or chemiluminescent immunoassay). The rate of excretion is calculated from the concentration over time.

Common Conditions Affecting Results

Conditions like liver disease, gallstones, or bile duct strictures can alter bile acid excretion. Chronic liver conditions, metabolic disorders, or medications may also influence results.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Bile acid excretion rate

Frequently asked questions

What does a low bile acid excretion rate mean?
A low rate may suggest impaired liver function, bile duct blockage, or other conditions affecting bile flow. Your provider will discuss findings with you based on your symptoms and medical history.
How often is this test repeated?
Frequency depends on your condition. Some patients need follow-up tests every few months to monitor changes, while others may only need it once.
Can diet affect this test result?
Dietary changes (e.g., high-fat meals) may temporarily influence bile acid levels, so your provider may advise fasting or specific timing for the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy