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Serum or plasma concentration of total protein (mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein status and kidney function.

Quick summary

["Total protein levels can signal kidney health or protein loss from other sources."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61353-9
Short code
LPT 10 ug PHA Bld
Synonyms
LPT 10 ug PHA Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like kidney disease, liver problems, malnutrition, or protein loss due to conditions like burns or chronic illness. It can also help monitor treatment responses or diagnose unexplained weight loss or swelling.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Avoid smoking or strenuous activity for 30 minutes before drawing blood.

What Happens During the Test?

A healthcare professional will insert a small needle into a vein in your arm to draw blood. You may feel a slight pinch, but the procedure usually takes less than 5 minutes. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are reported in grams per deciliter (g/dL). Low levels may indicate malnutrition, kidney disease, or liver problems, while very high levels could suggest dehydration, inflammation, or conditions like multiple myeloma.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein levels are a key marker for assessing protein balance in the body. Low protein levels can signal kidney dysfunction (e.g., nephrotic syndrome), liver disease (e.g., cirrhosis), or severe malnutrition. High protein levels may reflect dehydration, chronic inflammation, or certain cancers. Monitoring these levels helps guide treatment for underlying conditions and supports long-term health management.

Short name

Total Protein

Frequently asked questions

What does a low total protein result mean?
A low total protein result may indicate conditions like kidney disease, liver problems, or malnutrition. Your doctor will review your symptoms, medical history, and other test results to determine the cause and next steps.
What does a high total protein result mean?
A high total protein result could suggest dehydration, chronic inflammation, or certain medical conditions like multiple myeloma. Your healthcare provider will discuss further testing or evaluations to understand the reason.
Can diet affect total protein test results?
Yes, diet can influence protein levels. Eating a balanced diet rich in protein may temporarily raise protein levels, while fasting or certain medical conditions can lower them. Your doctor may recommend dietary adjustments or additional testing if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy