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Serum/plasma concentration of total protein by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein levels and kidney function.

Quick summary

["Total protein helps evaluate hydration, kidney health, and protein synthesis in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58729-5
Short code
LPT 2.5 ug PHA Act/Nor Bld
Synonyms
LPT 2.5 ug PHA Act/Nor Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like dehydration, kidney disease, liver problems, or malnutrition. It can also help monitor treatments for these conditions.

What Does a Low or High Protein Level Mean?

Low protein levels might indicate kidney issues, severe dehydration, or malnutrition. High protein levels could suggest dehydration, liver disease, or certain medical conditions like multiple myeloma.

How Is This Test Performed?

A blood sample is drawn from a vein in your arm. The sample is sent to a lab where it is analyzed using a nephelometry method to measure protein concentration.

What Are Common Reference Ranges?

While reference ranges can vary by lab, typical values for total protein in serum/plasma are usually between 6.0 to 8.0 grams per deciliter (g/dL).

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein levels are important for diagnosing and managing several health conditions. Low protein levels can signal kidney problems, poor nutrient absorption, or severe illness. High protein levels may indicate dehydration, liver disease, or conditions that cause excessive protein production in the body.

Short name

Total Protein

Frequently asked questions

What does a normal total protein level mean?
A normal total protein level suggests your body is producing and maintaining adequate protein levels, which are essential for many bodily functions. However, it doesn’t rule out underlying conditions that might affect protein metabolism.
Can diet affect my total protein test results?
Yes, your diet can influence protein levels. Eating a balanced diet rich in protein can help maintain normal levels, but extreme dietary changes or conditions like malnutrition can affect results.
How often should I get this test?
The frequency of this test depends on your health status and any conditions you have. Your healthcare provider will determine how often you need it based on your individual needs and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy