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###1: Lupus Anticoagulant Phospholipid-Dependence Test (40 µg/mL Phospholipid), Whole Blood

Published: August 9, 2026Updated: August 16, 2026

###3: This test checks for lupus anticoagulant, an antiphospholipid antibody that can interfere with clotting tests in the laboratory. It does not necessarily mean that you have an antiphospholipid syndrome.

Quick summary

["###4: A positive result may be associated with an increased risk of blood clots, but it must be interpreted with symptoms, other laboratory results, and repeat testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61354-7
Short code
LPT 40 ug PHA Bld
Synonyms
LPT 40 ug PHA Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.5
Ref high
12
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

###5: What the test measures

###6: Lupus anticoagulant is an immune substance directed against phospholipid-binding proteins. The laboratory evaluates whether the sample prolongs a phospholipid-dependent clotting reaction and whether that effect is corrected with confirmatory testing.

###7: How the test is performed

###8: A whole-blood sample is collected and processed according to the laboratory’s validated procedure. Because clotting assays are sensitive to sample handling, timing, and reagent conditions, the laboratory may use more than one testing method or a confirmation step.

###9: Understanding the result

###10: A result may be reported as negative, positive, or indeterminate. An indeterminate result can occur with inadequate sample handling or interfering anticoagulant treatment and may require repeat testing.

###11: Preparation and medications

###11: Tell your clinician and laboratory about anticoagulant or antiplatelet medicines, recent bleeding, pregnancy, autoimmune disease, and any recent blood-thinning procedures. Do not stop prescribed medication without medical advice.

Reference range

Adult: 4.5-12.0 μg/dLN/A

Specimen: whole-blood

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

###2: Lupus anticoagulant test

Frequently asked questions

###14: Does a positive result mean I have antiphospholipid syndrome?
###15: No. Diagnosis generally requires compatible clinical findings and persistently positive antiphospholipid laboratory testing on appropriately timed samples. Your clinician will interpret the result in your medical context.
###16: Why might the test need to be repeated?
###17: Confirmation helps distinguish a persistent finding from a temporary or analytical effect. Testing may need to be repeated at least 12 weeks later when clinical circumstances support evaluation for antiphospholipid syndrome.
###18: Can medicines affect the result?
###19: Yes. Anticoagulant and antiplatelet medicines can interfere with the assay, while some other medicines can cause lupus anticoagulant to be present temporarily. Inform the laboratory about all medicines and supplements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy