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Hemoglobin A1c (HbA1c) with 24-hour urine collection for creatinine clearance calculation

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar over the past 2–3 months and helps assess kidney function with a urine sample.

Quick summary

["Helps track diabetes management and kidney health together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58728-7
Short code
LPT 5 ug PHA Act/Nor Bld
Synonyms
LPT 5 ug PHA Act/Nor Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters for Diabetes Management

HbA1c reflects long-term blood sugar control, while creatinine clearance evaluates kidney function. Together, they provide a clearer picture of how well your body is managing both glucose and waste removal.

How the Test Works

Your blood sample is tested for HbA1c levels, which indicate average blood sugar over months. A 24-hour urine sample measures creatinine, a waste product from muscle metabolism, to estimate kidney function.

What to Expect During the Test

A fingerstick blood draw (for HbA1c) and a timed urine collection (for creatinine) are required. Follow your healthcare provider’s instructions for proper urine sample timing and handling.

Common Causes for Testing

This test may be ordered if you have diabetes to monitor treatment effectiveness, if kidney function is suspected, or if you’re at risk for complications like kidney disease.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c + CrCl (24h urine)

Frequently asked questions

What does an abnormal result mean?
High HbA1c levels (above target) suggest poor blood sugar control, while abnormal creatinine clearance may indicate kidney strain. Both findings warrant discussion with your doctor to adjust treatment plans.
How often should I get this test?
Typically, HbA1c is checked every 3–6 months for diabetes management. Creatinine clearance may be part of routine kidney assessments or if symptoms arise.
Can diet or medications affect these results?
Yes—high-protein diets or certain medications (e.g., NSAIDs) can temporarily alter creatinine levels. HbA1c may be affected by recent blood sugar fluctuations or medications like insulin or sulfonylureas.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy