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Serum or Plasma Creatinine Concentration (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test checks kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81757-7
Short code
LPT IL-2 max/CD3 NFr Bld FC
Synonyms
LPT IL-2 max/CD3 NFr Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Your kidneys normally filter waste products, including creatinine, from your blood. High levels may indicate kidney problems, while low levels could suggest dehydration or muscle breakdown. This test is often used alongside other kidney function tests to monitor overall kidney health.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood. If you’re on a low-protein diet or have had recent muscle activity, let your provider know, as these can affect results.

Common Causes of Abnormal Results

High creatinine levels may signal kidney disease, dehydration, or conditions like heart failure or severe muscle damage. Low levels might suggest dehydration, overhydration, or certain liver or muscle disorders. Always discuss any changes with your healthcare team.

When This Test Might Be Ordered

Your doctor may order this test to check kidney function before surgeries, during pregnancy, if you have symptoms like fatigue, swelling, or frequent urination, or if you have a history of kidney issues.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is a key part of diagnosing and monitoring kidney disease, helping providers track how well your kidneys are working over time. It’s also used to assess kidney function in people with diabetes, high blood pressure, or other chronic conditions.

Short name

Creatinine

Frequently asked questions

What does a ‘normal’ creatinine level mean for me?
A ‘normal’ result doesn’t mean your kidneys are perfectly healthy—it just means your creatinine level falls within the typical range for your age, sex, and body size. Your doctor will consider this along with other tests and your overall health to interpret results.
Can diet or exercise affect my creatinine test results?
Yes, eating a high-protein diet or intense exercise can temporarily raise creatinine levels. If you’re unsure, ask your provider whether to adjust your diet or activity level before the test.
How often should I get this test?
Your doctor will determine how often you need this test based on your health status. Regular monitoring may be recommended if you have kidney disease, diabetes, or other conditions affecting kidney function.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy