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CD4 T-Cell Count (Absolute)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of CD4 cells (a type of white blood cell) in your blood. CD4 cells help the immune system fight infections.

Quick summary

["CD4 cells are key to your immune health; lower counts may signal immune weakness."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81755-1
Short code
LPT IL-2 max/CD45 NFr Bld FC
Synonyms
LPT IL-2 max/CD45 NFr Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order a CD4 count to monitor your immune system, especially if you have HIV, an autoimmune condition, or are undergoing treatments that affect immunity. It can also help track how well your immune system is responding to treatment or disease progression.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, similar to a routine blood draw. The process usually takes a few minutes.

What the Results Mean

Results are typically reported as a count of CD4 cells per microliter (cells/µL) of blood. While specific ranges vary by lab, lower counts often indicate a weakened immune system, which can increase risk for infections.

Common Conditions Monitored

A CD4 count is often used to diagnose and manage HIV/AIDS, track immune recovery in cancer treatments, or evaluate conditions like lupus or other autoimmune diseases.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: CD4 counts are critical for assessing immune function. Very low counts (often below 200 cells/µL) may indicate severe immune deficiency, increasing vulnerability to infections or cancers. Regular monitoring helps guide treatment decisions.

Short name

CD4 Count

Frequently asked questions

What does a low CD4 count mean?
A low CD4 count suggests your immune system may not be functioning as well as it should. This can happen with certain illnesses (like HIV), treatments (like chemotherapy), or autoimmune conditions. Your doctor will discuss what your results mean in the context of your health.
How often should I get this test?
Your doctor will determine how often you need this test based on your medical history, current treatments, and overall health. For example, people with HIV may get tests more frequently to monitor their immune status.
Can I eat or drink before this test?
You can eat and drink normally before this test. No special preparation is required, but avoid heavy meals just before the blood draw if you experience dizziness or lightheadedness afterward.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy