Serine concentration in cerebrospinal fluid (CSF)
This test measures the amount of serine, an amino acid, found in your spinal fluid. Serine plays a role in brain function and metabolism, and its levels can sometimes be checked to help diagnose certain neurological conditions.
["Serine in CSF may be evaluated when symptoms of brain or nerve issues are present."]
Key facts at a glance
- LOINC
- 79601-1
- Short code
- L-serine CSF-sCnc
- Synonyms
- L-serine CSF-sCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may recommend this test if you have symptoms like headaches, vision changes, weakness, or numbness that could suggest conditions like meningitis, brain tumors, or other neurological disorders. It may also be part of a broader evaluation for metabolic or genetic disorders affecting amino acids.
What Does This Test Involve?
A small amount of cerebrospinal fluid is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then analyzed in a lab to measure serine concentration. This is typically done under sterile conditions to ensure accuracy.
What Does a Result Mean?
While reference ranges can vary by lab, abnormal serine levels in CSF might indicate conditions affecting brain chemistry or fluid balance. For example, high levels could be linked to certain metabolic disorders or genetic conditions, while low levels may suggest other underlying issues.
What Are Possible Causes of Abnormal Results?
Changes in serine levels in CSF can be influenced by genetic disorders (like aminoacidopathies), metabolic diseases, or conditions that alter brain chemistry. It’s important to discuss your symptoms and medical history with your doctor to understand the full context of your results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: When This Test May Help Diagnose or Guide Treatment
Short name
Serine CSF Level
Frequently asked questions
Could my test results affect my treatment plan?
What if my test results are normal?
How often will I need this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy