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Lipoprotein(a) [Lp(a)] concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of cholesterol-related protein linked to increased risk of heart disease and blood clots.

Quick summary

["Lipoprotein(a) levels help assess cardiovascular risk beyond traditional cholesterol measurements."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51000-8
Short code
L tropica IgG+IgM Ser-Imp
Synonyms
L tropica IgG+IgM Ser-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While cholesterol is well-known for heart health, lipoprotein(a) has its own distinct role. High levels may contribute to plaque buildup in arteries and increase the risk of serious conditions like heart attacks or strokes, even in people without high cholesterol.

Why Might You Need This Test?

Your healthcare provider may order this test if you have a family history of heart disease, stroke, or blood clots, or if you have conditions like high blood pressure, diabetes, or chronic kidney disease. It may also be used to monitor treatment for certain genetic or cardiovascular conditions.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis using an immunoassay method to measure lipoprotein(a) concentration.

What Do Results Mean?

Results are reported in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). While there are no universally accepted reference ranges for lipoprotein(a), higher levels are generally associated with increased cardiovascular risk. Your results will be interpreted in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated lipoprotein(a) levels are an independent risk factor for cardiovascular disease, including atherosclerosis (plaque buildup in arteries), coronary artery disease, and peripheral artery disease. Some studies suggest it may also play a role in other conditions like venous thrombosis (blood clots in veins). While lifestyle changes and medications can help manage cholesterol, lipoprotein(a) remains a focus for personalized cardiovascular risk assessment, particularly in high-risk individuals.

Short name

Lipoprotein(a) Level

Frequently asked questions

How often should I get this test?
The frequency of testing depends on your individual risk factors and medical history. Your healthcare provider will determine how often to check your lipoprotein(a) levels based on your overall health, family history, and any treatments you’re receiving.
What causes elevated lipoprotein(a) levels?
The exact cause of elevated lipoprotein(a) levels isn’t fully understood, but genetics play a major role. Some people inherit high levels from their family. Other factors, such as smoking, obesity, or certain medical conditions, may also influence levels, though they don’t always cause them to rise.
Can lifestyle changes lower lipoprotein(a) levels?
While lifestyle changes like quitting smoking, maintaining a healthy weight, and following a heart-healthy diet may help manage other cardiovascular risk factors, there’s limited evidence that they significantly lower lipoprotein(a) levels. Genetic factors are the primary driver, so treatments like medications (e.g., PCSK9 inhibitors) may be recommended for those with very high levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy