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Serum Ammonia Level (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of ammonia in your blood. Ammonia is a waste product your body creates when breaking down proteins, and high levels can signal potential liver or kidney issues.

Quick summary

["Ammonia levels help assess liver function and kidney health by detecting toxic buildup."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17049-8
Short code
Ltx Glv Ext Ammon IgE Bld Qn
Synonyms
Ltx Glv Ext Ammon IgE Bld Qn
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like confusion, fatigue, or nausea, or if they suspect liver disease (such as cirrhosis), liver failure, or kidney problems. It can also be part of routine monitoring for conditions like metabolic disorders or after liver surgery.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test to get more accurate results. Avoid consuming protein-rich foods or supplements for that time. Bring your test results or questions to your appointment.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it typically only takes a few minutes. The blood sample is then sent to a lab for analysis.

What Do the Results Mean?

Results are interpreted by your doctor based on your overall health and medical history. Very high or very low levels may indicate underlying conditions that need further evaluation, such as liver dysfunction or metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Ammonia Levels and Health

Short name

Ammonia Blood Test

Frequently asked questions

What Are Common Causes of High or Low Ammonia?
High ammonia levels can result from liver disease (including cirrhosis or hepatitis), kidney failure, or certain metabolic disorders. Low ammonia levels are less common but may occur in conditions like severe dehydration or certain genetic disorders.
How Often Should I Get This Test?
Your doctor will determine how often you need this test based on your health condition. If you have a chronic liver or kidney disease, regular monitoring may be recommended. Follow their guidance for scheduling.
Can I Take Anything to Lower My Ammonia Levels?
No over-the-counter supplements or medications can reliably lower ammonia levels on their own. Instead, focus on managing your underlying condition (e.g., liver/kidney health) with prescribed treatments, diet adjustments, or lifestyle changes as advised by your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy