Lipoprotein(a) [Lp(a)] concentration

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a distinct protein called apolipoprotein(a). While it shares some traits with regular cholesterol, it behaves differently in the body and is linked to higher risks of heart disease, particularly in arteries. Unlike other cholesterol types, lipoprotein(a) does not respond well to standard cholesterol-lowering medications like statins.

Why Might You Need This Test?

Your healthcare provider may order this test if you have a family history of heart disease, high cholesterol, or other risk factors. It may also be used to monitor conditions like atherosclerosis or to guide treatment plans for patients with elevated cardiovascular risks.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis using a specialized immunoassay method to measure lipoprotein(a) concentration.

What Does the Test Result Mean?

Results are typically reported in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). While exact reference ranges vary by lab, higher levels may indicate increased cardiovascular risk, though individual risk depends on other factors like age, lifestyle, and overall health.