Serum or plasma concentration of vascular endothelial growth factor (VEGF)

Why This Test Might Be Ordered

Your healthcare provider may order this test to assess blood vessel health, monitor conditions like cancer (e.g., kidney, lung, or eye cancers), or evaluate responses to treatments that affect blood flow or tumor growth. It could also be part of a broader evaluation for symptoms like fatigue, swelling, or changes in vision.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into a vein (typically in your arm) to draw blood. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

VEGF levels can vary widely depending on health status, disease activity, or treatment. High levels might suggest conditions like certain cancers or inflammation, while low levels could indicate vascular insufficiency or other circulatory issues. Your provider will interpret results in the context of your medical history and symptoms.

Common Conditions Monitored

This test is often used to monitor conditions such as solid tumors (e.g., renal cell carcinoma), age-related macular degeneration (AMD), or diabetic retinopathy. It may also help track responses to therapies like angiogenesis inhibitors.