Skip to content

Lymphocyte Count (Manual Blood Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell important for fighting infections and maintaining immune function.

Quick summary

["Lymphocytes help protect your body from illness and disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29261-5
Short code
Lymph Abn NFr Bld Manual
Synonyms
Lymph Abn NFr Bld Manual
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a lymphocyte count to diagnose or monitor conditions affecting the immune system, such as infections, autoimmune diseases, or certain cancers. It can also help assess how well your immune response is working after treatments like chemotherapy or radiation.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein (usually in your arm) to draw a blood sample. The process is quick and typically painless. If you’re nervous, let your healthcare provider know.

What the Test Results Mean

Results are usually reported as a count of lymphocytes per microliter (cells/µL) of blood. While reference ranges vary by lab, lower than expected counts may indicate immune suppression, while higher counts could suggest infection, inflammation, or certain diseases.

Common Conditions Monitored

Lymphocyte counts are tracked in conditions like leukemia, HIV/AIDS, lupus, rheumatoid arthritis, and after organ transplants. Abnormal levels may also signal chronic infections (e.g., tuberculosis) or reactions to medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lymphocyte Count

Frequently asked questions

How often will I need this test?
Your doctor will determine how often you need this test based on your health condition, treatment plan, or symptoms. Some patients may need it monthly, while others only occasionally.
Can lifestyle changes affect my lymphocyte count?
Yes, lifestyle factors like diet, sleep, and stress can influence immune function. While not all changes will alter your test results, maintaining a balanced diet, staying hydrated, and managing stress may support overall immune health.
What should I do if my lymphocyte count is unusually low?
If your count is below normal, your doctor may recommend further testing (e.g., blood cultures, immune function tests) or adjustments to your treatment plan. Follow-up may include monitoring for infections or evaluating underlying causes like vitamin deficiencies or chronic illness.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy