Lymphocyte count in cerebrospinal fluid (CSF)
This test measures the number of white blood cells called lymphocytes found in your spinal fluid. Lymphocytes are a type of immune cell that help protect your body from infections.
["Lymphocytes in spinal fluid can help diagnose or monitor certain conditions affecting the brain and spinal cord."]
Key facts at a glance
- LOINC
- 26475-4
- Short code
- Lymphocytes # CSF
- Synonyms
- Lymphocytes # CSF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you have symptoms like headaches, neck stiffness, fever, or neurological issues that could suggest an infection, inflammation, or other condition affecting the central nervous system. It might also be used to monitor treatment progress for conditions such as meningitis, multiple sclerosis, or certain cancers.
What to Expect Before the Test
You’ll typically have a small needle inserted into your lower back to collect a sample of spinal fluid. The procedure is usually quick and may cause mild discomfort, but you’ll be given local anesthesia to numb the area.
What the Test Results Mean
The results show the count of lymphocytes (a type of white blood cell) in the fluid. Elevated levels may indicate an infection, inflammation, or other immune-related conditions. Lower-than-expected levels might suggest certain neurological disorders or immune deficiencies.
Common Conditions Monitored
This test helps diagnose or track conditions like meningitis, encephalitis, multiple sclerosis, lymphoma, or other immune-related diseases affecting the central nervous system.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Elevated or Low Lymphocyte Counts
Short name
CSF Lymphocyte Count
Frequently asked questions
What Does a Normal Range Mean for Me?
How Often Should I Get This Test?
Can I Eat or Drink Before This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy