Skip to content

Lymphocyte Count by Manual Differential Blood Cell Count

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell, in your blood. It helps assess immune function and identify conditions affecting your immune system.

Quick summary

["This test helps doctors check if your immune system is working properly or if there’s an imbalance in your blood cell types."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71605-0
Short code
Lymphocytes NFr.DF Pcar Manual
Synonyms
Lymphocytes NFr.DF Pcar Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to evaluate immune health, diagnose conditions like infections, autoimmune diseases, or blood disorders, or monitor treatment responses. It’s often part of a complete blood count (CBC) but focuses specifically on lymphocytes.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw blood. The process usually takes a few minutes, and you may feel a brief pinch.

What the Test Results Mean

Results show the absolute number of lymphocytes per microliter of blood. Abnormal counts may suggest immune deficiencies, infections, or other health issues. Your doctor will interpret results in the context of your overall health.

Common Conditions Affecting Lymphocyte Counts

Low lymphocyte counts may indicate immune suppression, chronic illnesses, or certain medications. High counts can signal infections, inflammation, or overactive immune responses. These patterns often require further medical evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lymphocyte counts are critical for diagnosing and managing immune-related disorders. They help identify whether your body is overreacting to infections, underproducing immune cells, or responding to treatments like chemotherapy or steroids.

Short name

Manual Lymphocyte Count

Frequently asked questions

What causes a low lymphocyte count?
Low lymphocyte counts can result from infections (like HIV), autoimmune diseases, certain medications (e.g., steroids), or conditions that weaken the immune system, such as malnutrition or chronic illnesses like diabetes.
What causes a high lymphocyte count?
High lymphocyte counts often occur during infections (e.g., viral or bacterial), certain cancers (like lymphoma), or inflammatory conditions. Stress, emotional upset, or some medications may also temporarily raise counts.
How often should I get this test?
Your doctor will determine how often to check this test based on your symptoms, medical history, and treatment plan. Regular monitoring may be needed if you have ongoing health conditions affecting your immune system.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy