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Lymphocyte Count (Peripheral Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell, in your blood. Lymphocytes help fight infections and are part of your immune system.

Quick summary

["Your immune system’s white blood cell defenders are checked here."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26481-2
Short code
Lymphocytes NFr Plr
Synonyms
Lymphocytes NFr Plr
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a lymphocyte count to diagnose or monitor conditions affecting your immune system, such as infections, autoimmune diseases, or certain cancers. It can also help assess how well your body is responding to treatments like chemotherapy or immune-modifying therapies.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw a blood sample. The process usually takes a few minutes, and you may feel a brief pinch or slight discomfort. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results are typically reported as a count of lymphocytes per microliter (µL) of blood. While reference ranges vary by lab, low or high counts may signal underlying health concerns, such as infections, immune deficiencies, or certain cancers. Your doctor will interpret the results in the context of your overall health.

Common Conditions Affecting Lymphocyte Counts

Low lymphocyte counts (lymphocytopenia) might occur with infections, certain medications, or conditions like HIV/AIDS. High counts (lymphocytosis) can be seen in chronic infections, some cancers, or inflammatory diseases. Your doctor will consider symptoms and other test results to determine the cause.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lymphocyte counts are critical for diagnosing and managing immune-related disorders. Abnormal levels can indicate immune system dysfunction, infections, or underlying diseases that require targeted treatment. Regular monitoring helps track how well your immune response is functioning over time.

Short name

Lymphocyte Count

Frequently asked questions

What causes a low lymphocyte count?
Low lymphocyte counts can result from infections (like HIV or COVID-19), certain medications (e.g., steroids), autoimmune diseases, or conditions that weaken the immune system, such as chemotherapy or bone marrow disorders.
What causes a high lymphocyte count?
High lymphocyte counts often appear in chronic infections (e.g., tuberculosis), certain cancers (like lymphoma or leukemia), or inflammatory diseases. Stress, sleep deprivation, or certain medications may also temporarily raise levels.
How often should I get this test?
Frequency depends on your health needs. Doctors may recommend it during routine check-ups, after treatments for immune-related conditions, or if you have symptoms like frequent infections, fatigue, or unexplained weight loss.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy