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Lymphoma Acute Phase Screening Panel (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures key biomarkers to help detect or monitor acute lymphoma, a fast-growing cancer of the lymphatic system. It assesses proteins and substances that change during an acute flare-up.

Quick summary

["Early detection of lymphoma activity with critical blood markers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54227-4
Short code
Lymphoma - acute screen Pnl Spec FC
Synonyms
Lymphoma - acute screen Pnl Spec FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The panel typically includes tests for markers like C-reactive protein (CRP), which rises when inflammation or infection is present, and lactate dehydrogenase (LDH), which can indicate rapid cell turnover often seen in lymphoma. Other possible components may include albumin, ferritin, or other acute-phase reactants depending on the specific protocol used.

Why It’s Done

Doctors may order this test if you have symptoms like unexplained weight loss, fever, night sweats, or swollen lymph nodes. It’s also used during follow-up to check for disease progression or response to treatment.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate serum or plasma for testing. This sample is sent to a lab for analysis using methods like immunoassay or nephelometry.

What to Expect Before the Test

No special preparation is typically required, but inform your healthcare provider about any medications, supplements, or recent illnesses that could affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lymphoma Acute Phase Screen

Frequently asked questions

How elevated or low levels of these markers can signal lymphoma activity or other conditions, such as infections, autoimmune diseases, or other cancers. Results help guide treatment decisions or monitor disease progression.
This test alone cannot diagnose lymphoma. It’s often used alongside other tests, like imaging scans or biopsy results, for a complete evaluation.
What does a positive result mean?
A positive result may indicate inflammation, infection, or lymphoma activity. Your doctor will interpret results in the context of your symptoms, medical history, and other tests.
How often will I need this test?
Frequency depends on your treatment plan. During active treatment, tests may be done more often to monitor response. After treatment, follow-up tests help ensure lymphoma hasn’t returned.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy