Lymph Node Lymphocyte Subset Quantification by Flow Cytometry (with Specimen Identification)

What This Test Measures

Lymphocytes are a key part of your immune system, and this test identifies specific subsets (e.g., T-cells, B-cells, natural killer cells) by analyzing their characteristics in lymph fluid. The results help determine the balance and activity of these cells, which can be important for diagnosing conditions like infections, autoimmune diseases, or cancers.

Why It Might Be Ordered

Your doctor may order this test if you have symptoms like persistent infections, unexplained lymph node swelling, or if you’re undergoing treatment for a condition that affects immune cells. It can also be part of a broader evaluation for conditions like lymphoma, leukemia, or immune deficiencies.

Sample Collection and Preparation

Lymph fluid is typically collected from a lymph node or nearby tissue during a procedure called a lymph node biopsy. The sample is then analyzed using flow cytometry, a method that separates and counts different cell types based on their unique markers.

What to Expect Before the Test

You may need to avoid certain medications or fasting instructions, depending on the procedure. Your doctor will provide specific instructions based on your situation. The biopsy itself may cause mild discomfort or bruising, but recovery is usually quick.