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Lymphocyte count in whole blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell important for fighting infections and maintaining immunity. It helps assess immune function and identify conditions affecting lymphocyte levels.

Quick summary

["Lymphocytes help protect your body from infections and diseases by detecting and destroying harmful invaders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30120-0
Short code
Lymphs IgD # WBC
Synonyms
Lymphs IgD # WBC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to evaluate your immune system, diagnose conditions like infections, autoimmune diseases, or blood disorders, or monitor treatment responses for conditions such as leukemia or lymphoma.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or hand to draw blood. If you’re nervous, let your provider know—they can offer ways to make it more comfortable.

What the Test Results Mean

Results show the absolute lymphocyte count (typically in cells per microliter). Low levels may suggest immune suppression, high levels could indicate chronic infections or certain cancers. Always discuss results with your provider.

Common Conditions Affecting Lymphocyte Counts

Changes in lymphocyte counts can signal conditions like HIV/AIDS, lymphoma, or autoimmune diseases (e.g., lupus). They may also appear in response to infections, stress, or certain medications.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Lymphocyte counts are critical for diagnosing and managing immune-related disorders. Low counts may require immune support or treatment adjustments, while elevated counts could prompt further investigation into chronic infections or malignancies.

Short name

Lymphocyte Count (WBC Differential)

Frequently asked questions

What causes a low lymphocyte count?
Low lymphocyte counts can result from infections (like HIV), certain medications, autoimmune diseases, or conditions that weaken the immune system (e.g., chemotherapy).
What causes a high lymphocyte count?
High lymphocyte counts may occur with chronic infections (e.g., tuberculosis), certain cancers (like lymphoma), or inflammatory conditions. Stress or recent illness can also temporarily raise levels.
How often should I get this test?
Frequency depends on your health. Your provider may recommend it periodically if you have an ongoing condition affecting immunity, such as HIV, cancer, or autoimmune disorders. Follow-up tests are usually scheduled based on your treatment plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy